Antibacterial and cytotoxic effects of silver nanoparticles fabricated by Eryngium billarderi Delar. Extract

This study describes a facile synthesis of spherical silver nanoparticles (AgNPs) mediated by the extract of Eryngium billardieri Delar. with antibacterial and cytotoxicity studies using normal L-929 cell line. It is found that nanometer sized (31.72 nm), uniform and well dispersed AgNPs are obtained as shown by XRD, UV–Vis, FT-IR, DLS and TEM measurements. It is evidenced that the tested Gram–negative strains are readily controlled, such that MIC values of 50 and 200 µg/L are sufficient to inhibit them. The MTT cytotoxicity results indicate that the
effect of nanoparticle on L-929 cell line is time and dose dependent.